Collagen is the main protein of the connective tissue that constitutes 30% of all human proteins. This is the most important structural protein. Collagen is present in most tissues and organs, including bones, cartilage, skin, ligaments, tendons and the cornea. Collagen is made of amino acids, mainly glycine and proline, as well as hydroxyproline and hydroxylisin. The main task of collagen is to connect the cells, therefore, it is an important component for the internal organs. Collagen has a positive effect on the cartilage matrix.